生命科学与生物医学前沿:阿茨海默等疾病的细胞机制与发病原理研究

方向:理工

专业:公共卫生与医学

适合人群:免疫学,生物学,抗击冠状病毒,分子生物学,细胞与分子医学,生命科学,生物,医学

是否可以加论文:

项目时长及形式:英文

产出:

7周在线小组科研学习+5周论文指导学习 共125课时

学术报告

优秀学员获主导师Reference Letter

EI/CPCI/Scopus/ProQuest/Crossref/EBSCO或同等级别索引国际会议全文投递与发表(可用于申请)

结业证书

成绩单

项目介绍:

本项目将从细胞基础结构入手,探究内质网内稳态,内质网的结构和功能,人类疾病中的ER应激和未展蛋白质反应,分析细胞死亡模式和疾病之间的关系,自噬性的调节在人类疾病中的作用等。项目以阿尔茨海默氏病、帕金森氏病等神经退行性疾病,Cov-19为例,带领学生探究细胞机制与疾病发病之间的关系。通过本项目的学习,学生将进一步了解维持细胞正常形态结构、功能和代谢的重要意义,在项目结束时提交报告,进行成果展示。

个性化研究课题参考:

脂质组学揭示病毒感染引起的脂代谢异常及潜在治疗靶点

血管平滑肌细胞收缩的分子机制研究进展

细胞焦亡参与动脉粥样硬化形成的分子机制新进展

This project will start with the cellular infrastructure, explore the homeostasis of the endoplasmic reticulum, the structure and function of the endoplasmic reticulum, the ER stress and unexpanded protein response in human diseases, and analyze the relationship between cell death patterns and diseases. The role of phagocytic regulation in human diseases, etc. The project takes Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases, Cov-19 as an example, and leads students to explore the relationship between cell mechanisms and disease onset. Through the study of this project, students will further understand the importance of maintaining the normal shape, structure, function and metabolism of cells, and submit a report at the end of the project to demonstrate the results.

Suggested Future Research Fields:

Lipidomics reveals abnormal lipid metabolism caused by viral infection and potential therapeutic targets

Research progress on the molecular mechanism of vascular smooth muscle cell contraction

New progress in the molecular mechanism of pyroptosis involved in the formation of atherosclerosis

生命科学与生物医学前沿:阿茨海默等疾病的细胞机制与发病原理研究

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